Rabies in Cats
What is rabies?
Rabies is a viral disease that can infect all warm-blooded animals, including cats and people, although some species are somewhat naturally resistant to the disease. When signs of rabies occur, it is an almost invariably fatal disease.
Rabies has been recognized and described since approximately 2300 BC.
How widespread is rabies?
Rabies occurs in every continent except Australia and Antarctica. Most countries are affected.
The majority of countries that are rabies-free are islands. Here is a list of currently accepted rabies-free countries or islands:
Ireland (Republic of)
St. Martin (Netherlands Antilles)
St. Pierre et Miquelon Islands
Turks and Caicos Islands
These rabies-free countries have relied on strict quarantine laws to keep the disease out, and particularly to stop the virus getting into the wildlife of those countries. Great Britain and some other rabies-free countries have recently changed their quarantine regulations for fully vaccinated and microchip identifiable cats and dogs that meet certain conditions.
How is the virus transmitted?
Rabies virus does not survive long outside a mammal's body. The virus can be shed in the saliva of infected animals and bite wounds that inject saliva beneath the skin are the usual means of transmission of infection. In North America the skunk, raccoon, fox and bat are important reservoirs whereas in Europe foxes are the main source of infection for people and other animals. In Asia, Africa and Latin America the main reservoir is not wildlife but stray, free-roaming dogs. In these areas, human infection is more common.
How long is the incubation period between a bite from an infected animal and the appearance of symptoms in the cat?
This can vary from ten days to one year or longer. Incubation in the cat is generally less than in the dog and is typically three to eight weeks. Death usually occurs within ten days from the first onset of signs.
The speed at which clinical signs develop depends upon:
1. The site of infection. The nearer the bite is to the brain and spinal cord, the quicker the virus reaches the nervous tissue and causes symptoms.
2. The severity of the bite.
"Rabies virus is not always present in saliva of an infected animal."
3. The amount of virus injected by the bite. Rabies virus is not always present in saliva of an infected animal.
What are the clinical signs of Rabies?
Following a bite or scratch from a rabid animal, the disease progresses through three stages:
1. In the first or prodromal stage, there is a marked change in temperament; quiet cats become agitated and can become aggressive, while active extroverts may become nervous or shy.
2. This phase is then followed by so-called furious rabies that is by far the most common type in the cat. During this phase, excitement predominates and it is at this stage that the cat is most dangerous, both to other animals and to the owner. The cat becomes increasingly nervous, irritable and vicious. Muscle spasms will often prevent swallowing and there is excessive drooling of saliva.
3. The third stage is the paralytic stage, which usually occurs after about seven days. Ultimately the cat will become comatose and die.
A noted feature of the condition in cats is the widely dilated pupil throughout all stages of the disease.
How is Rabies diagnosed?
"Rabies can only be diagnosed by direct examination of the brain."
Rabies can only be diagnosed by direct examination of the brain. It is not possible to diagnose this disease in a living animal. If there is a high suspicion that the animal has rabies, or if an animal showing symptoms of rabies dies suddenly, your veterinarian may recommend submission of the appropriate brain samples for testing.
Is it possible to survive a bite from a rabid animal?
In some cases, there is no rabies virus in the saliva at the time the rabid animal bites another. In this situation, the bitten animal will not develop rabies. However, once the symptoms of rabies develop, the disease will almost invariably progress to death.
"It is possible to interrupt the progression from an infected bite to the onset of signs by the early post-bite use of anti-rabies serum."
There are very rare and poorly documented cases where people or animals have recovered. However, as Louis Pasteur was the first to show, it is possible to interrupt the progression from an infected bite to the onset of signs by the early post-bite use of anti-rabies serum. This antiserum contains specific immune antibodies to the virus. The most important method for preventing the progression of rabies is by administering an immediate dose of rabies vaccine. The vaccine stimulates the bitten animal to develop its own neutralizing antibodies to the rabies virus.
Is post-bite vaccination always effective in people?
"The anti-rabies antibodies produced by post-bite vaccination are only effective if administered before the rabies virus enters the nervous system."
The anti-rabies antibodies produced by post-bite vaccination are only effective if administered before the rabies virus enters the nervous system. Once in nerve cells, the virus spreads along the nerve fibers, where it is protected from antibody attack. Therefore, the early use of vaccine is important in people that are exposed, or potentially exposed, to a rabid animal. Of course, for people that are likely to be exposed to rabies because of their career, such as veterinarians and wildlife control officers, it is preferable to be vaccinated in advance.
Is post-bite vaccination used in exposed cats?
Because of the potential risk to people, an unvaccinated exposed cat that has bitten or scratched a human should not normally be given either antiserum or vaccine, because it may mask signs of infection. If there is a high probability of exposure, the safest policy is to euthanize the animal; the alternative is strict quarantine for many months.
If the exposed cat has previously been vaccinated then a booster vaccination is indicated followed by a period of at least thirty days of quarantine and careful observation.
What is the treatment for Rabies?
"There is no treatment for a cat with rabies infection."
There is no treatment for a cat with rabies infection. If rabies is suspected the cat has to be kept in quarantine and prevented from escaping or injuring someone. Your veterinarian is required by law to notify the animal disease regulatory authorities.
Can I catch rabies?
Yes, the disease is zoonotic, meaning it can be transmitted from an animal to man. However, it is only transmitted by the bite of a rabid animal. The virus is present in the saliva of the infected animal only for a limited time.
"...seek the advice of a doctor without delay."
If you are bitten by any animal that may be rabid, you should immediately wash the wound thoroughly with soap and water and seek the advice of a doctor without delay. Suspicious animals include stray or feral dogs or cats and any wild animal, particularly if the animal is showing unusual behavior such as lack of fear of people, excessive salivation, or aggression. Post-exposure rabies treatment with serum or vaccine may be recommended and is very successful if given immediately after exposure.
Should my cat be vaccinated?
Yes. Rabies vaccination is required by law in most states and provinces. Rabies vaccination of cats is important for your safety as well as your cats. Rabies vaccines are very effective and are usually given to kittens at three to four months of age. Depending on your state or provincial laws, and the advice of your veterinarian, revaccination will be recommended at specific intervals.
Are there any ill effects from rabies vaccination?
Rabies vaccines are safe and there is no risk of the vaccine causing rabies. The formation of lumps or cancers (sarcomas) has been associated with some types of killed vaccines including rabies vaccines, but this is still unproven and controversial. These cases are extremely rare. As with all vaccines, the individual cat may show some transient mild side effects in the day or so following vaccination. These may include some lethargy and inappetence. If your cat shows more pronounced signs including difficulty in breathing this could indicate an allergic reaction to one or more components of the vaccine and you should call your veterinarian at once.
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