Adverse Reactions to Food in Dogs

What is the difference between food allergies and adverse reactions to food in dogs? 

adverse-reactions-to-food-in-dogsTraditionally, the terms “food allergy” and “food intolerance” have been used to describe any and all adverse food reactions in dogs.  These terms are really most accurately applied when the immune system is involved in creating the signs and symptoms that result.  A far more accurate term to describe adverse food reactions in dogs is “food intolerance.”  Food intolerance covers a large category of adverse food reactions that do not involve the immune system.

Adverse food reactions in dogs often mimic food allergies because there are only so many ways that the body can demonstrate a problem with food.  One characteristic of food intolerance is that it occurs on the initial exposure to that food or food additive.  Reactions regulated by the immune system generally require several exposures before signs are seen.  The incidence of food intolerance versus food allergy is not known. 

What are the different kinds of adverse food reactions that can happen to dogs?

There are several general categories of food reactions that may occur in dogs:

Food poisoning

Food poisoning is an adverse reaction caused by the direct action of a food on the dog.  Food poisoning is a frequent cause of GI disease in dogs and may include the following:

  • Ingestion of excessive amounts of a specific nutrient like vitamin A or vitamin D
  • Scavenging of putrefied food
  • Ingestion of specific problematic foods like chocolate
  • Ingestion of plants that can cause GI irritation like rhubarb


Food additives

Adverse reactions to food additives are frequently reported in people and include compounds like sulfites, monosodium glutamate, and certain spices.  Despite an impression that food additives can cause problems in dogs, data are lacking.  One food additive that can cause problems is disulfide.  Disulfides are found in onions and can cause damage to red blood cells.


Drug-like reactions to food

Histamine, which can cause sometimes severe clinical reactions in humans – flushing, diarrhea, sweating, nausea, vomiting, and facial swelling – may not be an issue for dogs in general, except for the occasional individual reaction.



There are several important disorders of carbohydrate intolerance in humans.  Recognized carbohydrate intolerance in dogs is less frequent.  One fairly common carbohydrate reaction in dogs is lactose intolerance.  The signs include diarrhea, bloating, and abdominal discomfort after ingesting cow’s or goat’s milk.


Dietary indiscretion

Dogs are famous for eating things they shouldn’t, including articles of clothing!  Gluttony and garbage ingestion are frequent causes of adverse dietary reactions.  The gastrointestinal signs may result from bacterial contamination, fat or grease, or from bones, wood, plastic, or aluminum foil.


It is important to distinguish between a dog’s adverse reaction to something he has eaten versus involvement of the immune system and a potential food sensitivity.  Food sensitivity or food allergy typically results in skin and GI signs that require a comprehensive approach to restore the body to a state of balance.  Knowing the dog’s feeding schedule, nutrient profile, and the timing and severity of any signs and symptoms will help your veterinarian distinguish between a one-time adverse food reaction and a food hypersensitivity.


This client information sheet is based on material written by: Robin Downing, DVM, CVPP, CCRP, DAAPM

© Copyright 2015 LifeLearn Inc. Used and/or modified with permission under license.

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